From Principles to Protection: How to Operationalize AI Safety and Security

By
June 3, 2025

Bridging Frameworks to Function in AI Safety and Security - A Practical Guide

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Introduction: The Headlines Are Already Here

As generative AI becomes more deeply embedded in consumer experiences, the risks associated with its misuse are growing more complex and consequential.

In the past year, a major nonprofit was forced to shut down its AI-powered chatbot after it began dispensing harmful advice that contradicted its core mission of supporting health and recovery. More recently, a prominent tech company faced backlash when its celebrity-themed AI assistant engaged in sexually explicit conversations with users posing as minors, raising urgent concerns around safety and content moderation.

And it’s not just about technical “glitches” that generate dangerous outputs. Malicious actors are actively exploiting AI systems to produce harmful content, bypass safety controls, and scale their influence. From synthetic exploitation and algorithmic manipulation to prompt injection and model jailbreaks, the threat landscape is expanding rapidly, while the margin for error continues to shrink.

The question is no longer if misuse will occur, but whether your organization is equipped to detect, prevent, and respond when it does.

Despite this urgency, organizations of all sizes, from medium-sized organizations and nonprofits to global enterprises, are racing to adopt AI technologies. In doing so, many overlook the foundational safeguards needed to deploy these systems responsibly. As recent PR crises have shown, the consequences of deploying AI without proper protections can be reputational, ethical, and even legal.

In response, the concept of “Responsible AI” has surged into the spotlight. Governments are drafting regulations. Industry bodies are publishing guidelines. Major LLM providers have released extensive frameworks and best practices, each outlining principles for safe and ethical AI development. “Responsible AI” has become a buzzword. 

But with all the frameworks, codes of conduct, and aspirational language, one question remains: How do you actually execute on it? What does it take to translate principles into day-to-day safeguards, policies, and infrastructure? That’s where many organizations get stuck — and where our latest guide steps in.

What This Report Covers (and Why You Should Read It)

To help enterprise leaders and AI practitioners take a practical step towards having truly responsible AI systems, ActiveFence has released the new “Bridging Frameworks to Function in AI Safety and Security,” a practical guide to safe AI deployment. 

This resource provides a clear, actionable roadmap for operationalizing AI safety at scale. Drawing on our work with top foundation models, extensive adversarial testing, and global monitoring of evolving abuse tactics, the guide outlines six essential strategies to embed safety into AI systems from day one.

Inside, you’ll find:

  • A breakdown of emerging threats
    Learn how the rise of multimodal models, persistent-memory agents, and internet-connected systems is reshaping the AI risk landscape.
  • Real-world misuse cases
    Examine actual incidents of deepfake disinformation, synthetic CSAM, and the growing industrialization of AI-powered abuse.
  • Best practices for red teaming and evaluation
    Explore how to simulate attacks, test system integrity, and close feedback loops using both structured and freestyle adversarial techniques.
  • Guidance on building adaptive safety policies
    Create “living” policies that evolve with new threats, regional nuances, and changing abuse patterns.
  • Data hygiene and the “bad data cycle”
    Avoid cascading vulnerabilities by improving data quality, diversity, and recency in training and evaluation pipelines.
  • When and how to partner with experts
    Understand the limitations of in-house safety teams—and how to extend your capabilities with external partners who specialize in threat detection and mitigation.

Whether you’re leading platform integrity, AI policy, or product safety, this guide offers practical tools to stay ahead of bad actors and safeguard innovation without slowing it down.

Download the Report

Your AI systems are evolving. Your safety strategy should evolve with them.
Download “Bridging Frameworks to Function in AI Safety and Security” to learn how to future-proof your systems against evolving threats.

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Table of Contents

Bridging Frameworks to Function in AI Safety and Security - A A Practical Guide

Download the report.